Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.72 |
| ▸ | NMBR | P28336 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 4/20 | 0.61 |
| ▸ | MME | P08473 | 3/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876669 | 1.00 | TACR1 (0.72) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL11870726 | 1.00 | TACR1 (0.72) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL1285921 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL3808330 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL220800 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL29401760 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL29386277 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL29935468 | 0.92 | NMBR (0.76) | NMBRMAPTGAAHTTECE1 | |
| SCHEMBL5403959 | 0.92 | MME (0.69) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL11865865 | 0.90 | TACR1 (0.67) | TACR1NMBRMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000297-A | GASTROENTERIC ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1976-12-28 | — | — | US | disclosed |