Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.33 |
| ▸ | MEN1 | O00255 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | TNKS | O95271 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864731 | 0.77 | TLR8 (0.38) | NPSR1CYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL19242816 | 0.65 | GRM2 (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL11326239 | 0.64 | KMT2A (0.53) | NPSR1KDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL11853173 | 0.61 | MEN1 (0.51) | NPSR1CYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL11872645 | 0.60 | MAPT (0.43) | NPSR1CYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL11861254 | 0.59 | ELANE (0.33) | ALDH1A1HTT | |
| SCHEMBL24804491 | 0.59 | ATM (0.36) | — | |
| SCHEMBL14026861 | 0.59 | DPP4 (0.40) | KDM4EALDH1A1MAPTRAB9ATSHR | |
| SCHEMBL15131095 | 0.59 | KMT2A (0.56) | KDM4EALDH1A1SMN1; SMN2RXFP1HSD17B10 | |
| SCHEMBL11865130 | 0.59 | KDM4E (0.54) | NPSR1KDM4EALDH1A1SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987196-A | FUNGISTATS | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |