Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069450 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL4152470 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9756736 | 0.87 | AKT1 (0.53) | SMN1; SMN2ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL10582461 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL9354751 | 0.83 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL15794505 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL8532390 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1557403 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL28631055 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPT | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDLMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931268-A | Methylhydrazinomethyl-substituted benzoic acid amides | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |