Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868898 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHPGDABCB1NPC1 | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL7694380 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL14031385 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL250619 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL6896134 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL26296065 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL9611293 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDABCB1MAPK1 | |
| SCHEMBL20716127 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDABCB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300189-B1 | New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5223489-A | Treatment of ypertension and heart failure | UJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5142048-A | Enzyme inhibitor; carbamoyl group-containing acids | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4921855-A | New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0300189-A2 | New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |