Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269427 | 0.86 | ALDH1A1 (0.48) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL21436765 | 0.85 | ALDH1A1 (0.47) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL30308949 | 0.84 | CYP3A4 (0.55) | CYP3A4ALDH1A1CA2LMNAMMP9 | |
| SCHEMBL4011150 | 0.84 | ALDH1A1 (0.48) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL28646685 | 0.83 | ALDH1A1 (0.48) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL430999 | 0.79 | LTA4H (0.53) | CYP3A4ALDH1A1LMNAMAPK1L3MBTL1 | |
| SCHEMBL19924884 | 0.78 | PRSS1 (0.40) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL22710209 | 0.78 | LTA4H (0.51) | CYP3A4ALDH1A1CA2LMNAPRSS1 | |
| SCHEMBL1726211 | 0.77 | LTA4H (0.53) | CYP3A4ALDH1A1LMNAMAPK1LTA4H | |
| SCHEMBL6471180 | 0.77 | PRSS1 (0.36) | CYP3A4ALDH1A1CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933733-A | Phosphite stabilized polyvinyl chloride containing resins | KYODO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | claimed |
| US-3933733-A | Phosphite stabilized polyvinyl chloride containing resins | KYODO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |