Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858611 | 0.87 | MAPT (0.65) | MAPTGAAALDH1A1PBRM1ATM | |
| SCHEMBL78116 | 0.85 | ALDH1A1 (0.62) | MAPTGAAALDH1A1CA12CA1 | |
| SCHEMBL29409634 | 0.81 | CA12 (0.70) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL689217 | 0.81 | CA12 (0.70) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL28135536 | 0.81 | ALDH1A1 (0.62) | MAPTGAAALDH1A1PBRM1ATM | |
| SCHEMBL10937897 | 0.80 | MAPT (0.74) | MAPTGAAALDH1A1CA1CA2 | |
| SCHEMBL6917724 | 0.78 | MAPT (0.66) | MAPTGAAALDH1A1PBRM1ATM | |
| SCHEMBL1913492 | 0.78 | MAPT (0.55) | MAPTGAAALDH1A1PBRM1ATM | |
| SCHEMBL8956410 | 0.78 | GAA (0.55) | MAPTGAAALDH1A1PBRM1ATM | |
| SCHEMBL5741534 | 0.78 | MAPT (0.55) | MAPTGAAALDH1A1PBRM1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658937-A | A kind of bicyclic alkaloid compound and its preparation method and application | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| US-3979411-A | FUNGICIDES, INSECTICIDE, MITICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |