SCHEMBL11869686

SCHEMBL11869686

CCC(CC)Nc1c([N+](=O)[O-])cc(C)c(Cl)c1[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HCAR3 P49019 2/20 0.42
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
MAPT P10636 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
VCAM1 P19320 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
HTT P42858 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11434187 0.87 ALDH1A1 (0.65) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL14690957 0.87 L3MBTL1 (0.49) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL21821 0.87 L3MBTL1 (0.49) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL29392877 0.87 L3MBTL1 (0.49) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL8373915 0.87 L3MBTL1 (0.49) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL8057686 0.86 L3MBTL1 (0.48) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL27926297 0.86 L3MBTL1 (0.48) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
Pendimethalin SCHEMBL20723668 0.86 L3MBTL1 (0.48) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
SCHEMBL11073392 0.84 ALDH1A1 (0.47) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9
SCHEMBL11447986 0.84 ALDH1A1 (0.47) ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3968138-A HERBICIDE UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1976-07-06 US disclosed