Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13366481 | 0.85 | SIGMAR1 (0.51) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL11870243 | 0.82 | OPRD1 (0.52) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL3403111 | 0.81 | SIGMAR1 (0.72) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL2360466 | 0.81 | SIGMAR1 (0.72) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL2360468 | 0.81 | SIGMAR1 (0.72) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL11864088 | 0.80 | SIGMAR1 (0.54) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL14650822 | 0.77 | PRCP (0.64) | SIGMAR1 | |
| SCHEMBL12622887 | 0.76 | TMEM97 (0.40) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL13337793 | 0.76 | CYP2D6 (0.44) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL19689049 | 0.75 | SIGMAR1 (0.42) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | claimed |