Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B2 | P80365 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SHBG | P04278 | 3/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872240 | 1.00 | HSD11B2 (0.54) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11874700 | 0.89 | CYP3A4 (0.64) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11874693 | 0.89 | CYP3A4 (0.64) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11876574 | 0.86 | CYP3A4 (0.71) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11877677 | 0.86 | LMNA (0.51) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11877669 | 0.86 | LMNA (0.51) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11876565 | 0.86 | CYP3A4 (0.71) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11877459 | 0.85 | LMNA (0.66) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11877453 | 0.85 | LMNA (0.66) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 | |
| SCHEMBL11876777 | 0.84 | NR3C2 (0.52) | HSD11B2SMN1; SMN2NR3C2HSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966713-A | 11β-FLUOROANDROSTENES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| US-3966713-A | 11β-FLUOROANDROSTENES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |