Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.66 |
| ▸ | AR | P10275 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | SHBG | P04278 | 3/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | SNCA | P37840 | 2/20 | 0.66 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.66 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.66 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877453 | 1.00 | LMNA (0.66) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL619054 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL10185506 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL3362406 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL619055 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL24900243 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL14525631 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL20058468 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL15920491 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 | |
| SCHEMBL20058563 | 0.88 | SMN1; SMN2 (0.76) | LMNACYP19A1ARHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966713-A | 11β-FLUOROANDROSTENES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| US-3966713-A | 11β-FLUOROANDROSTENES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |