Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP4 | P49662 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 7/20 | 0.51 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872436 | 1.00 | CASP1 (0.51) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL11863118 | 0.97 | IL23R (0.51) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL11863142 | 0.97 | IL23R (0.51) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL11869107 | 0.96 | IL23R (0.50) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL11870578 | 0.92 | IL23R (0.49) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL11869131 | 0.91 | IL23R (0.49) | CASP1CASP3CASP4CASP5CASP7 | |
| SCHEMBL24120770 | 0.90 | CXCR4 (0.55) | CXCL8TACR1CTSLCTSSCTSK | |
| SCHEMBL11872216 | 0.88 | GNRHR (0.50) | CTSLCTSSCTSKCTSHACE | |
| SCHEMBL11867492 | 0.86 | GNRHR (0.51) | IL23RCTSLCTSSCTSKCTSH | |
| Teprotide SCHEMBL11855843 | 0.86 | F13A1 (0.52) | IL23RCTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3973006-A | Peptide enzyme inhibitors of angiotensin I | E. R. SQUIBB & SONS, INC. (US) | 1976-08-03 | — | — | US | disclosed |