Teprotide

Teprotide

SCHEMBL11855843

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.52

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ F13A1 P00488 2/20 0.52
▸ TGM2 P21980 2/20 0.52
▸ CXCR4 P61073 2/20 0.51
▸ APLNR P35414 2/20 0.50
▸ ABCC2 Q92887 1/20 0.49
▸ GNRHR P30968 1/20 0.49
▸ PTGS1 P23219 1/20 0.49
▸ CTSL P07711 2/20 0.48
▸ CTSS P25774 2/20 0.48
▸ CTSK P43235 2/20 0.48
▸ CTSH P09668 1/20 0.48
▸ CTNNB1 P35222 1/20 0.48
▸ IL23R Q5VWK5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Teprotide SCHEMBL613590 1.00 F13A1 (0.52) F13A1TGM2CXCR4APLNRABCC2
Teprotide SCHEMBL8158703 0.97 CXCR4 (0.51) F13A1TGM2CXCR4APLNRABCC2
SCHEMBL11872216 0.96 GNRHR (0.50) F13A1TGM2CXCR4APLNRABCC2
SCHEMBL11867492 0.94 GNRHR (0.51) F13A1TGM2CXCR4APLNRABCC2
Teprotide SCHEMBL613757 0.92 GNRHR (0.57) F13A1TGM2APLNRABCC2GNRHR
SCHEMBL11863118 0.89 IL23R (0.51) F13A1TGM2CXCR4CTSLCTSS
SCHEMBL11863142 0.89 IL23R (0.51) F13A1TGM2CXCR4CTSLCTSS
SCHEMBL24120770 0.87 CXCR4 (0.55) CXCR4CTSLCTSSCTSKCTSH
SCHEMBL11865471 0.86 CXCR4 (0.46) F13A1TGM2CXCR4APLNRABCC2
SCHEMBL11872436 0.86 CASP1 (0.51) CXCR4CTSLCTSSCTSKCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3947575-A Peptides as argiotensin converting enzyme inhibitors E. R. SQUIBB & SONS, INC. (US) 1976-03-30 — — US claimed
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2018-06-14 — — US disclosed
US-3973006-A Peptide enzyme inhibitors of angiotensin I E. R. SQUIBB & SONS, INC. (US) 1976-08-03 — — US disclosed
US-3947575-A Peptides as argiotensin converting enzyme inhibitors E. R. SQUIBB & SONS, INC. (US) 1976-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180164289-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 F13A1 2652/4885TGM2 1002/4885CXCR4 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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