Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823055 | 0.82 | MAPT (0.41) | MAPTFAAHCHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL1439109 | 0.80 | MAPT (0.41) | MAPTFAAHCHRM2CHRM4CHRM5 | |
| SCHEMBL14887223 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL14989441 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL4634192 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL14887474 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL14989440 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL15574890 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL14887353 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 | |
| SCHEMBL11878704 | 0.79 | MAPT (0.41) | MAPTCA1CA2CA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941823-A | NITROSATION OF AN IMIDO-ESTER OR -THIOESTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-03-02 | — | — | US | disclosed |