Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1439109 | 0.98 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL8861409 | 0.82 | SLC7A5 (0.43) | MAPTSLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL8861407 | 0.82 | SLC7A5 (0.43) | MAPTSLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL11874247 | 0.82 | MAPT (0.37) | MAPTFAAHCHRM2CHRM4CHRM5 | |
| SCHEMBL28936255 | 0.81 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1SLC7A5CHRM1 | |
| SCHEMBL14887353 | 0.80 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1FAAH | |
| SCHEMBL15574890 | 0.80 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1FAAH | |
| SCHEMBL14989440 | 0.80 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1FAAH | |
| SCHEMBL14989441 | 0.80 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1FAAH | |
| SCHEMBL14887474 | 0.80 | MAPT (0.41) | MAPTSLC1A3SLC1A2SLC1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429310-A | Continuous preparation method of 2-amino malonamide | 大连理工大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-106632029-A | Process for synthesizing rebamipide | 大桐制药（中国）有限责任公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105968786-A | Athletic ground runway material | 丁悦 | 2016-09-28 | — | — | CN | disclosed |
| CN-105968968-A | Flame-retardant and antibacterial coating for safety protective garment | 王乔 | 2016-09-28 | — | — | CN | disclosed |
| CN-105802574-A | Adhesive for communication optical cable mounting and preparation method of adhesive | 王义金 | 2016-07-27 | — | — | CN | disclosed |
| CN-105295353-A | Binder for casting and preparation method thereof | SUZHOU JIEDERUI PREC MACHINERY CO LTD | 2016-02-03 | — | — | CN | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| EP-2099803-A1 | HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS | Alantos Pharmaceuticals Holding, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| EP-2094707-A1 | HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS | Alantos Pharmaceuticals Holding, Inc. (US) | 2009-09-02 | — | — | EP | disclosed |
| CN-101410120-A | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES INC (US) | 2009-04-15 | — | — | CN | disclosed |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. | 2006-09-07 | — | — | US | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1663254-A2 | ANTI-INFLAMATORY PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| US-5693772-A | PROTECTING ACID AND HYDROXY GROUPS OF BENANOMICIN A, REDUCTION OF AMIDE TO IMIDOESTER WITH MEERWEIN REAGENT, DEPROTECTING, REFLUXING IN ACETONE/WATER MIXTURE TO CLEAVE IMIDOESTER AND FORM CARBOXY GROUP | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5686449-A | 1,5-benzodiazepines useful as gastrinor CCK-antagonists | GLAXO WELLCOME S.P.A. (IT) | 1997-11-11 | — | — | US | disclosed |
| EP-0695297-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-07 | — | — | EP | disclosed |
| EP-0684253-A1 | DESALANINEBENANOMICIN A DERIVATIVE AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994025445-A1 | 1,5-BENZODIAZEPINES USEFUL AS GASTRIN OR CCK-ANTAGONISTS | GLAXO S.P.A. (IT) | 1994-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | MAPT 4426/4885SLC1A3 3829/4885SLC1A2 3764/4885 |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | MAPT 2574/4885SLC1A3 3575/4885SLC1A2 4126/4885 |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | PHOSPHO1, TNF, PTGES | MAPT 2574/4885SLC1A3 3575/4885SLC1A2 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.