Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818538 | 0.91 | PPARG (0.62) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL28407544 | 0.90 | ATM (0.76) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL12857011 | 0.89 | PPARG (0.67) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL28407181 | 0.88 | PPARG (0.76) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL12869021 | 0.86 | PPARG (0.67) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL28465800 | 0.84 | PPARG (0.63) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL11881278 | 0.83 | PPARG (0.67) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL6135221 | 0.82 | PPARG (0.69) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL9102046 | 0.81 | PPARG (0.69) | PPARGTSHRLMNABLMCYP2C9 | |
| SCHEMBL27513111 | 0.81 | PPARG (1.00) | PPARGTSHRLMNABLMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932658-A | Composition and method for lower blood sugar containing N-[4-(β-<2-methoxy-5-chloro-benzamido>-ethyl)-benzenesulfonyl]-N'-cyclopentyl-urea | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |