Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881278 | 0.99 | PPARG (0.67) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL13486392 | 0.88 | PPARG (0.71) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28407544 | 0.86 | ATM (0.76) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28905340 | 0.85 | PPARG (0.64) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL23736042 | 0.85 | ADORA3 (0.74) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL28407181 | 0.84 | PPARG (0.76) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL27513111 | 0.82 | PPARG (1.00) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL11874263 | 0.81 | PPARG (0.69) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL12857049 | 0.81 | PPARG (0.62) | PPARGADORA3ALDH1A1LMNATSHR | |
| SCHEMBL24162709 | 0.81 | PPARG (0.65) | PPARGADORA3ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120737058-A | Hesperetin derivative, and preparation method and application thereof | 江西呐博酒业有限公司 | 2025-10-03 | — | — | CN | disclosed |
| CN-111793011-B | Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof | 山东大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-112250604-B | Hapten and artificial antigen for broad-spectrum detection of sulfonylurea drugs, antibody and application thereof | 华南农业大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-112250604-A | Hapten and artificial antigen for broad-spectrum detection of sulfonylurea drugs, antibody and application thereof | 华南农业大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-111793011-A | Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof | 山东大学 | 2020-10-20 | — | — | CN | disclosed |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | CHEN JAMES M | 2009-05-21 | — | — | US | disclosed |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | CHEN JAMES M | 2009-05-21 | — | — | US | disclosed |
| US-7407965-B2 | Phosphonate analogs for treating metabolic diseases | GILEAD SCIENCES, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407965-B2 | Phosphonate analogs for treating metabolic diseases | GILEAD SCIENCES, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-5576436-A | FLUORESCENT LABELED LIGANDS FOR MEASUREMENT OF RECEPTORS | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |
| US-4379785-A | Heterocyclic substituted sulfonyl ureas, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-12 | — | — | US | disclosed |
| US-4379153-A | Benzenesulfonyl ureas, and pharmaceutical preparations | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-05 | — | — | US | disclosed |
| US-4325963-A | ANTIDIABETIC AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4157395-A | TREATMENT OF DIABETES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-05 | — | — | US | disclosed |
| US-4153710-A | HYPOGLYCEMIC AGENTS | STAROGARDZKIE ZAKLADY FARMACEUTYCZNE POLFA (PL) | 1979-05-08 | — | — | US | disclosed |
| US-4132795-A | Benzenesulfonyl ureas and their use for the treatment of diabetes mellitus | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | PHOSPHO1, G6PC1, PC | PPARG 314/4885ADORA3 1674/4885ALDH1A1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.