Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 7/20 | 0.75 |
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407181 | 0.93 | PPARG (0.76) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL11874263 | 0.90 | PPARG (0.69) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL12857011 | 0.89 | PPARG (0.67) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL12869021 | 0.89 | PPARG (0.67) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL9102046 | 0.86 | PPARG (0.69) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL28536164 | 0.86 | ATM (1.00) | ATMPPARGTSHRSMN1; SMN2EPHX1 | |
| SCHEMBL28465800 | 0.86 | PPARG (0.63) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL27513111 | 0.86 | PPARG (1.00) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL11881278 | 0.85 | PPARG (0.67) | ATMPPARGTSHRLMNABLM | |
| SCHEMBL6135221 | 0.84 | PPARG (0.69) | ATMPPARGTSHRLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | claimed |
| CN-112578045-B | Detection method for simultaneously determining content of 8 compounds in glipizide drugs | 山东则正医药技术有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112578045-A | Detection method for simultaneously determining content of 8 compounds in glipizide drugs | 山东则正医药技术有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | disclosed |