SCHEMBL11876949

SCHEMBL11876949

COc1ccc(/C=C/C=C/C=C/C=C/C=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
CYP2A6 P11509 1/20 0.57
CYP3A4 P08684 2/20 0.55
KDM4E B2RXH2 2/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
TRPA1 O75762 1/20 0.53
RELA Q04206 1/20 0.53
F3 P13726 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
STAT3 P40763 1/20 0.53
ESR1 P03372 2/20 0.52
CYP1A2 P05177 2/20 0.52
ABL1 P00519 1/20 0.52
TTR P02766 1/20 0.52
CYP1A1 P04798 1/20 0.52
ABCB1 P08183 1/20 0.52
ALOX5 P09917 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566691 1.00 ALDH1A1 (0.57) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL11875764 1.00 ALDH1A1 (0.57) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL11875760 1.00 ALDH1A1 (0.57) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL566692 1.00 ALDH1A1 (0.57) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL11876953 1.00 ALDH1A1 (0.57) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
Para-Methoxy Cinnamaldehyde SCHEMBL514958 0.92 ALDH1A1 (0.61) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
Para-Methoxy Cinnamaldehyde SCHEMBL547945 0.92 ALDH1A1 (0.61) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
Para-Methoxy Cinnamaldehyde SCHEMBL1046275 0.92 ALDH1A1 (0.61) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL2830674 0.89 KDM4E (0.67) ALDH1A1CYP2A6CYP3A4KDM4ELMNA
SCHEMBL2449266 0.87 KDM4E (0.70) ALDH1A1CYP2A6CYP3A4KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3947337-A α,ω-Diarylpolyene photosensitizers for sulfonylazide polymers THE UPJOHN COMPANY (US) 1976-03-30 US disclosed