SCHEMBL2449266

SCHEMBL2449266

COc1ccc(/C=C/C=C/c2ccc(OC)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
CYP3A4 P08684 2/20 0.70
LMNA P02545 2/20 0.70
ALDH1A1 P00352 2/20 0.70
TP53 P04637 1/20 0.70
TSHR P16473 1/20 0.70
TRPA1 O75762 1/20 0.67
RELA Q04206 1/20 0.67
CYP1A2 P05177 4/20 0.64
CYP1A1 P04798 4/20 0.64
CYP1B1 Q16678 4/20 0.64
ESR1 P03372 2/20 0.64
PTGS2 P35354 2/20 0.64
NFE2L2 Q16236 2/20 0.64
AHR P35869 2/20 0.64
ABL1 P00519 1/20 0.64
TTR P02766 1/20 0.64
ABCB1 P08183 1/20 0.64
ALOX5 P09917 1/20 0.64
BCR P11274 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2449268 1.00 KDM4E (0.70) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL2830674 0.97 KDM4E (0.67) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL2622563 0.91 TRPA1 (0.83) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL15932969 0.91 KDM4E (0.72) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL2622580 0.91 RELA (0.83) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL8672323 0.91 TRPA1 (0.83) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL631998 0.89 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL13790336 0.89 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL4881152 0.89 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53
SCHEMBL699458 0.89 RELA (0.81) KDM4ECYP3A4LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
EP-2102708-B1 CURABLE COMPOSITION, COLOR FILTER, AND MANUFACTURING METHOD OF THE SAME FUJIFILM CORP (JP) 2018-05-16 EP disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
EP-0747461-B1 Polymer stabilized liquid crystals and flexible devices thereof SNIARICERCHE S C P A (IT) 2001-09-05 EP disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0803525-A2 Chiral anisotropic thermosets (cat) in polymer stabilized liquid crystals Sniaricerche S.C.P.A. (IT) 1997-10-29 EP disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
US-4250053-A WITH FLUORESCENT COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-02-10 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed