Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878534 | 0.97 | TSHR (0.56) | TSHRSMN1; SMN2MEN1KMT2APRKAG1 | |
| SCHEMBL11881125 | 0.92 | TSHR (0.64) | TSHRSMN1; SMN2MEN1KMT2APRKAG1 | |
| SCHEMBL11850946 | 0.82 | TSHR (0.70) | TSHRSMN1; SMN2MEN1KMT2APRKAG1 | |
| SCHEMBL11851828 | 0.79 | TSHR (0.72) | TSHRMEN1KMT2APRKAG1PRKAA1 | |
| SCHEMBL11874037 | 0.78 | TSHR (0.58) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11850062 | 0.76 | TSHR (0.86) | TSHRMEN1KMT2APRKAG1PRKAA1 | |
| SCHEMBL11877618 | 0.76 | ALDH1A1 (0.43) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11843146 | 0.75 | SOS1 (0.74) | TSHRMEN1KMT2APRKAG1PRKAA1 | |
| SCHEMBL2493279 | 0.73 | TSHR (0.83) | TSHRSMN1; SMN2MEN1KMT2APRKAG1 | |
| SCHEMBL11881579 | 0.71 | TSHR (0.64) | TSHRSMN1; SMN2MEN1KMT2APRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978059-A | BRONCHODILATOR AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |