Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851828 | 0.96 | TSHR (0.72) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL2493279 | 0.91 | TSHR (0.83) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11850062 | 0.88 | TSHR (0.86) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11843146 | 0.87 | SOS1 (0.74) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11845293 | 0.82 | TSHR (1.00) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11877505 | 0.82 | TSHR (0.55) | TSHRKMT2AMEN1SOS1PRKAG1 | |
| SCHEMBL11847278 | 0.81 | TSHR (0.80) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11842852 | 0.81 | TSHR (0.80) | TSHRKMT2AMEN1GAAGFER | |
| Hydrochloric Acid SCHEMBL11845788 | 0.81 | TSHR (0.78) | TSHRKMT2AMEN1GAAGFER | |
| SCHEMBL11850698 | 0.79 | TSHR (0.59) | TSHRKMT2AMEN1SOS1PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |