SCHEMBL11877973

SCHEMBL11877973

COc1ccccc1N/N=C1/C(=O)C=Cc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 5/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPK1 P28482 4/20 0.42
POLB P06746 3/20 0.42
TOP1 P11387 1/20 0.41
ALDH1A1 P00352 6/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
PKM P14618 2/20 0.39
BCHE P06276 1/20 0.39
PTPRC P08575 1/20 0.39
THRB P10828 1/20 0.39
IDO1 P14902 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
PTPN1 P18031 1/20 0.39
ACHE P22303 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875491 1.00 MAPT (0.43) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL340350 1.00 MAPT (0.43) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL9108481 0.86 POLB (0.44) MAPTMAPK1POLBALDH1A1KMT2A
SCHEMBL2389884 0.82 ALDH1A1 (0.42) MAPTKDM4EPOLBALDH1A1KMT2A
SCHEMBL11880063 0.78 MAPT (0.39) MAPTL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL10021593 0.78 GRM1 (0.33) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL11968417 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL30702588 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL11876684 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL333149 0.75 ALDH1A1 (0.49) MAPTL3MBTL1KDM4EMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed