SCHEMBL340350

SCHEMBL340350

COc1ccccc1N/N=C1\C(=O)C=Cc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 5/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPK1 P28482 4/20 0.42
POLB P06746 3/20 0.42
TOP1 P11387 1/20 0.41
ALDH1A1 P00352 6/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
PKM P14618 2/20 0.39
BCHE P06276 1/20 0.39
PTPRC P08575 1/20 0.39
THRB P10828 1/20 0.39
IDO1 P14902 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
PTPN1 P18031 1/20 0.39
ACHE P22303 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11875491 1.00 MAPT (0.43) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL11877973 1.00 MAPT (0.43) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL9108481 0.86 POLB (0.44) MAPTMAPK1POLBALDH1A1KMT2A
SCHEMBL2389884 0.82 ALDH1A1 (0.42) MAPTKDM4EPOLBALDH1A1KMT2A
SCHEMBL11880063 0.78 MAPT (0.39) MAPTL3MBTL1KDM4EPOLBALDH1A1
SCHEMBL10021593 0.78 GRM1 (0.33) MAPTL3MBTL1KDM4EMAPK1POLB
SCHEMBL11968417 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL30702588 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL11876684 0.77 KDM4E (0.40) MAPTKDM4EMAPK1POLBALDH1A1
SCHEMBL333149 0.75 ALDH1A1 (0.49) MAPTL3MBTL1KDM4EMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010054441-A1 NANOPIGMENTS NVA IP HOLDINGS PTY LTD (AU) 2010-05-20 WO claimed
US-12570902-B2 Storage stable liquid fugitive colored fire-retardant concentrates PERIMETER SOLUTIONS LP (US) 2026-03-10 US disclosed
US-20260041949-A1 Liquid Concentrate Fire Retardant Compositions Containing Mixtures of Ammonium Phosphates PERIMETER SOLUTIONS LP 2026-02-12 US disclosed
US-12478817-B2 Liquid concentrate fire retardant compositions containing mixtures of ammonium phosphates PERIMETER SOLUTIONS LP (US) 2025-11-25 US disclosed
US-20250108658-A1 INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS Prism Inks, Inc. (US) 2025-04-03 US disclosed
EP-3660087-B1 METHOD AND MATERIAL FOR THE PRODUCTION OF THREE-DIMENSIONAL OBJECTS BY ENERGY IMPULSE-INDUCED TRANSFER PRINTING IVOCLAR VIVADENT AG (LI) 2024-05-29 EP disclosed
EP-4320198-A1 FIRE RETARDANT COMPOSITIONS AND OTHER COMPOSITIONS CONTAINING ONE OR MORE BIOPOLYMERS AND COLLOIDAL SILICA Perimeter Solutions LP (US) 2024-02-14 EP disclosed
US-20230321473-A1 LIQUID CONCENTRATE FIRE RETARDANT COMPOSITIONS CONTAINING MIXTURES OF AMMONIUM PHOSPHATES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-12 US disclosed
US-20230256652-A1 PROCESS FOR ENERGY-PULSE-INDUCED TRANSFER PRINTING IO TECH GROUP LTD. (GB) 2023-08-17 US disclosed
US-20230256651-A1 SUPPORT MATERIAL FOR ENERGY-PULSE-INDUCED TRANSFER PRINTING IO TECH GROUP LTD (GB) 2023-08-17 US disclosed
US-20090260165-A9 Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye BRUN GAELLE 2009-10-22 US disclosed
EP-2074986-A1 Process for treating hair fibres using polysiloxane/polyurea L'Oréal (FR) 2009-07-01 EP disclosed
US-20090155198-A1 PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA L'OREAL, S.A. (FR) 2009-06-18 US disclosed
US-20090155198-A1 PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA L'OREAL, S.A. (FR) 2009-06-18 US disclosed
US-20080184496-A1 Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye L'OREAL S.A. (FR) 2008-08-07 US disclosed
US-20080184496-A1 Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye L'OREAL S.A. (FR) 2008-08-07 US disclosed
EP-1935404-A1 Composition for dyeing keratinous fibres comprising a polysiloxane-polyurea block copolymer L'Oréal (FR) 2008-06-25 EP disclosed
EP-1935403-A2 Composition containing a compound x and a compound y, at least one of which is silicone, and a hydrophobic direct dye L'Oréal (FR) 2008-06-25 EP disclosed
US-20080127429-A1 Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer L'OREAL S.A. (FR) 2008-06-05 US disclosed
US-20080127429-A1 Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer L'OREAL S.A. (FR) 2008-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155198-A1 PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA PUF60, POLR1C, PCBP1 MAPT 652/4885L3MBTL1 3860/4885KDM4E 2130/4885
US-20260041949-A1 Liquid Concentrate Fire Retardant Compositions Containing Mixtures of Ammonium Phosphates FYN, GRN, SYK MAPT 50/4885L3MBTL1 2396/4885KDM4E 1468/4885
US-12570902-B2 Storage stable liquid fugitive colored fire-retardant concentrates AFF2, AFF1, NEFM MAPT 203/4885L3MBTL1 3321/4885KDM4E 1769/4885
US-20080127429-A1 Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer KRT18, PUF60, VIM MAPT 2016/4885L3MBTL1 3155/4885KDM4E 885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.