Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.76 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.76 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.76 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.76 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.76 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.76 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520652 | 0.83 | MAPT (0.64) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11876436 | 0.82 | GRIN2D (0.63) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5532892 | 0.82 | ALDH1A1 (0.71) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6720615 | 0.81 | SIGMAR1 (0.82) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL8873287 | 0.80 | SIGMAR1 (0.84) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4490833 | 0.80 | ALDH1A1 (0.68) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3271853 | 0.80 | ALDH1A1 (0.68) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Nitric Acid SCHEMBL3858360 | 0.79 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8874642 | 0.79 | SIGMAR1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1285405 | 0.78 | HTT (0.74) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |