Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876448 | 0.81 | GRIN2D (0.66) | PLAUPOLBNOS1GRIN2DGRIN3B | |
| Nitric Acid SCHEMBL3858362 | 0.78 | GRIN2D (0.63) | PLAUPOLBNOS1GRIN2DGRIN3B | |
| SCHEMBL7115248 | 0.78 | POLB (0.45) | POLBHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL4476092 | 0.78 | KMT2A (0.57) | PLAUPOLBHTTNOS1GRIN2D | |
| SCHEMBL11880304 | 0.78 | PLAU (0.54) | PLAUPOLBNOS1GRIN2DGRIN3B | |
| SCHEMBL2694958 | 0.78 | ALDH1A1 (0.55) | PLAUPOLBHTTNOS1GRIN2D | |
| SCHEMBL11878505 | 0.78 | PLAU (0.54) | PLAUPOLBNOS1GRIN2DGRIN3B | |
| SCHEMBL11877783 | 0.77 | HTT (0.59) | PLAUHTTNOS1GRIN2DGRIN3B | |
| SCHEMBL8085056 | 0.76 | MAPT (0.40) | POLBHTTNOS1GRIN2DGRIN3B | |
| SCHEMBL8085062 | 0.76 | MAPT (0.40) | POLBHTTNOS1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |