Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836840 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL31152344 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL1457307 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL11879065 | 0.80 | PLAU (0.60) | PLAUALDH1A1MAPK1KCNMA1MAPT | |
| SCHEMBL13237378 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL14139413 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL10644319 | 0.78 | PLAU (0.58) | PLAUALDH1A1MAPK1KCNMA1MAPT | |
| SCHEMBL13021472 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL28058401 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 | |
| SCHEMBL12926882 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |