Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522307 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL13237378 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL14139413 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL11692257 | 0.79 | TSHR (0.56) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL12926882 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL3836840 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL31152344 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL1457307 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL13021472 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL11879040 | 0.77 | PLAU (0.55) | ALDH1A1KDM4EMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143999-A | Have cytotoxicity and antimitotic compound and its application method | 酵活有限公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-105358174-B | Cytotoxic and antimitotic compounds and methods of use thereof | 酵活有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106459162-A | VAR2CSA-drug conjugates | 酵活有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105358174-A | Cytotoxic and antimitotic compounds and methods of use thereof | CT FOR DRUG RES AND DEV | 2016-02-24 | — | — | CN | disclosed |