Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884816 | 0.76 | CA1 (0.44) | LMNACA1CA12CA2CA7 | |
| SCHEMBL11882940 | 0.75 | CA1 (0.38) | CA1CA12CA2CA7CA13 | |
| SCHEMBL10514950 | 0.73 | LMNA (0.38) | LMNASMN1; SMN2TLR7GLP1RCA12 | |
| SCHEMBL7753780 | 0.71 | LMNA (0.52) | LMNASMN1; SMN2CA1CA12CA2 | |
| SCHEMBL24773616 | 0.70 | LMNA (0.43) | LMNASMN1; SMN2TLR7GLP1RCA1 | |
| SCHEMBL18067288 | 0.70 | LMNA (0.35) | LMNASMN1; SMN2TLR7GLP1RCA12 | |
| SCHEMBL11509596 | 0.70 | GLP1R (0.38) | LMNASMN1; SMN2TLR7GLP1RCA12 | |
| SCHEMBL11001021 | 0.70 | LMNA (0.35) | LMNASMN1; SMN2TLR7GLP1R | |
| SCHEMBL11426170 | 0.68 | PDE10A (0.47) | LMNASMN1; SMN2TLR7GLP1R | |
| SCHEMBL18893674 | 0.67 | GLP1R (0.36) | LMNASMN1; SMN2TLR7GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3817998-A | 2-AMINO AND SUBSTITUTED AMINO-4, 6-DIAMINO-5-PYRIMIDINESULFONAMIDES | SANDOZ AG | 1974-06-18 | — | — | US | disclosed |