Phosphonic Acid

Phosphonic Acid

SCHEMBL11880909

CCCCCCC(CC)CC.O=[PH](O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
ALDH1A1 P00352 3/20 0.48
CA2 P00918 2/20 0.44
ACE2 Q9BYF1 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
GPR84 Q9NQS5 5/20 0.43
FDPS P14324 3/20 0.43
FFAR1 O14842 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL2401623 1.00 LMNA (0.54) LMNAALDH1A1CA2ACE2PRSS1
Phosphonic Acid SCHEMBL28813732 1.00 LMNA (0.54) LMNAALDH1A1CA2ACE2PRSS1
Phosphonic Acid SCHEMBL9262594 1.00 LMNA (0.54) LMNAALDH1A1CA2ACE2PRSS1
Phosphonic Acid SCHEMBL7893269 1.00 LMNA (0.54) LMNAALDH1A1CA2ACE2PRSS1
Phosphonic Acid SCHEMBL11042967 0.98 ALDH1A1 (0.50) LMNAALDH1A1CA2ACE2PRSS1
Phosphonic Acid SCHEMBL11044392 0.91 ALDH1A1 (0.58) LMNAALDH1A1CA2FDPSTDP1
Phosphonic Acid SCHEMBL11043674 0.91 LMNA (0.58) LMNACA2ACE2GPR84FDPS
Phosphonic Acid SCHEMBL11046062 0.88 LMNA (0.56) LMNAALDH1A1CA2ACE2GPR84
Phosphonic Acid SCHEMBL9262134 0.88 LMNA (0.56) LMNAALDH1A1CA2ACE2GPR84
Phosphonic Acid SCHEMBL11043177 0.88 LMNA (0.56) LMNAALDH1A1CA2ACE2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3952089-A WATER STRIPPING, FREEZING DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-04-20 US disclosed