Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645232 | 0.86 | KDM4E (0.58) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL13430811 | 0.85 | LMNA (0.62) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL27823277 | 0.83 | KDM4E (0.56) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL3029800 | 0.82 | HCRTR1 (0.62) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL11345796 | 0.82 | LMNA (0.72) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL11441352 | 0.82 | LMNA (0.72) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL1257635 | 0.81 | ALDH1A1 (0.71) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL9969762 | 0.81 | TSHR (0.61) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL5052356 | 0.80 | LMNA (0.53) | KDM4EKMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL2389931 | 0.80 | HSP90AA1 (0.58) | KDM4EKMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959359-A | VASODILATORS | LABORATOIRES LAROCHE NAVARRON (FR) | 1976-05-25 | — | — | US | disclosed |