Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887289 | 0.87 | RAB9A (0.49) | L3MBTL1ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL25207618 | 0.83 | APLNR (0.42) | GAANPSR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26922770 | 0.80 | PARP10 (0.47) | PARP10GAANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14480252 | 0.79 | NQO1 (0.42) | PARP10ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL14480364 | 0.79 | NQO1 (0.42) | PARP10ALDH1A1KMT2AMAPTTSHR | |
| Hydrochloric Acid SCHEMBL7383075 | 0.78 | PARP10 (0.46) | PARP10GAANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1051991 | 0.77 | SMN1; SMN2 (0.55) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL1077616 | 0.77 | SMN1; SMN2 (0.55) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL5742023 | 0.76 | SMN1; SMN2 (0.53) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7321879 | 0.76 | SMN1; SMN2 (0.53) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160333381-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-11-17 | — | — | US | disclosed |
| US-9434968-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150079640-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-03-19 | — | — | US | disclosed |
| US-8921079-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | disclosed |