SCHEMBL11887115

SCHEMBL11887115

CCCc1ccc(N(c2ccc(-c3ccc(N(c4ccc(CCC)cc4)c4ccc(C)c(C)c4)cc3)cc2)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.43
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
MAPT P10636 3/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GFER P55789 1/20 0.37
HRH3 Q9Y5N1 2/20 0.37
S1PR1 P21453 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CTSK P43235 1/20 0.36
RARB P10826 1/20 0.36
CHRNA7 P36544 2/20 0.36
CHRNA10 Q9GZZ6 2/20 0.36
CHRNA9 Q9UGM1 2/20 0.36
FFAR4 Q5NUL3 1/20 0.36
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13868118 1.00 MCL1 (0.43) MCL1LPLLIPGNISCHMAPT
SCHEMBL18286377 0.95 MCL1 (0.40) MCL1LPLLIPGNISCHMAPT
SCHEMBL13868115 0.95 MCL1 (0.40) MCL1LPLLIPGNISCHMAPT
SCHEMBL10471942 0.95 LPL (0.42) MCL1LPLLIPGMAPTNPC1
SCHEMBL11887124 0.90 RARB (0.45) NISCHMAPTRARBCHRNA7CHRNA10
SCHEMBL2260320 0.90 RARB (0.45) NISCHMAPTRARBCHRNA7CHRNA10
SCHEMBL14281447 0.90 MCL1 (0.37) MCL1LPLLIPGNISCHMAPT
SCHEMBL13868117 0.90 CNR2 (0.39) MCL1LPLLIPGNPC1RAB9A
SCHEMBL18286394 0.89 RARB (0.40) MCL1LPLLIPGNISCHMAPT
SCHEMBL2312776 0.87 S1PR1 (0.41) MCL1MAPTHRH3S1PR1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120189948-A1 CHARGE TRANSPORT FILM, ORGANIC ELECTRONIC DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed
US-20120189948-A1 CHARGE TRANSPORT FILM, ORGANIC ELECTRONIC DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2012-07-26 US disclosed