SCHEMBL2260320

SCHEMBL2260320

CCCCc1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccc(CCCC)cc5)c5ccc(C)c(C)c5)cc4)cc3)cc2)c2ccc(C)c(C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.45
SKP2 Q13309 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HSD11B1 P28845 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA10 Q9GZZ6 2/20 0.41
CHRNA9 Q9UGM1 2/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RARA P10276 1/20 0.40
MAPT P10636 1/20 0.40
MTOR P42345 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11887124 1.00 RARB (0.45) RARBSKP2CA1CA2HSD11B1
SCHEMBL5061273 0.95 SKP2 (0.47) SKP2CA1CA2CYP3A4CYP2D6
SCHEMBL12593387 0.95 SKP2 (0.47) SKP2CA1CA2CYP3A4CYP2D6
SCHEMBL11887110 0.95 SKP2 (0.47) SKP2CA1CA2CYP3A4CYP2D6
SCHEMBL25445746 0.90 LPL (0.47) RARBSKP2CA1CA2CYP3A4
SCHEMBL13868118 0.90 MCL1 (0.43) RARBNISCHCHRNA7CHRNA10CHRNA9
SCHEMBL11887115 0.90 MCL1 (0.43) RARBNISCHCHRNA7CHRNA10CHRNA9
SCHEMBL12593394 0.88 SKP2 (0.41) RARBSKP2CA1CA2HSD11B1
SCHEMBL12316361 0.88 AKT2 (0.41) RARBSKP2CHRNA7CHRNA10CHRNA9
SCHEMBL11887125 0.88 RARB (0.43) RARBSKP2CA1CA2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1933206-B1 Imaging member XEROX CORP (US) 2011-08-03 EP claimed
US-7799497-B2 Silanol containing overcoated photoconductors XEROX CORPORATION (US) 2010-09-21 US claimed
US-7592110-B2 Polyhydroxy siloxane photoconductors XEROX CORPORATION (US) 2009-09-22 US claimed
US-7514191-B2 Imaging member XEROX CORPORATION (US) 2009-04-07 US claimed
US-20080318146-A1 Imaging member having high charge mobility XEROX CORPORATION (US) 2008-12-25 US claimed
US-20080193866-A1 Polyhydroxy siloxane photoconductors XEROX CORPORATION 2008-08-14 US claimed
US-20080138724-A1 Imaging member XEROX CORPORATION (US) 2008-06-12 US claimed
US-20080107985-A1 Silanol containing overcoated photoconductors XEROX CORPORATION 2008-05-08 US claimed
US-20070254223-A1 IMAGING MEMBER XEROX CORPORATION 2007-11-01 US claimed
US-8236469-B2 Single layer photoreceptor comprising high mobility transport mixtures XEROX CORPORATION (US) 2012-08-07 US disclosed
US-20110195353-A1 SINGLE LAYER PHOTORECEPTOR COMPRISING HIGH MOBILITY TRANSPORT MIXTURES XEROX CORPORATION (US) 2011-08-11 US disclosed
US-7745082-B2 Imaging member XEROX CORPORATION (US) 2010-06-29 US disclosed
US-7745082-B2 Imaging member XEROX CORPORATION (US) 2010-06-29 US disclosed
US-7745082-B2 Imaging member XEROX CORPORATION (US) 2010-06-29 US disclosed
US-20080138724-A1 Imaging member XEROX CORPORATION (US) 2008-06-12 US disclosed
US-20080138724-A1 Imaging member XEROX CORPORATION (US) 2008-06-12 US disclosed
US-20080138724-A1 Imaging member XEROX CORPORATION (US) 2008-06-12 US disclosed
US-20070254223-A1 IMAGING MEMBER XEROX CORPORATION 2007-11-01 US disclosed
US-20070254223-A1 IMAGING MEMBER XEROX CORPORATION 2007-11-01 US disclosed
US-20070254223-A1 IMAGING MEMBER XEROX CORPORATION 2007-11-01 US disclosed