Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889803 | 1.00 | PKM (0.51) | PKML3MBTL1NPC1RAB9ASNCA | |
| SCHEMBL2452211 | 0.88 | SMN1; SMN2 (0.49) | PKML3MBTL1MAPTTP53TSHR | |
| SCHEMBL4134491 | 0.88 | SMN1; SMN2 (0.49) | PKML3MBTL1MAPTTP53TSHR | |
| SCHEMBL2452227 | 0.85 | PKM (0.46) | PKML3MBTL1NPC1RAB9ASNCA | |
| SCHEMBL2452210 | 0.85 | PKM (0.46) | PKML3MBTL1NPC1RAB9ASNCA | |
| SCHEMBL18664648 | 0.79 | PKM (0.60) | PKML3MBTL1NPC1RAB9ASNCA | |
| SCHEMBL18664977 | 0.78 | SNCA (0.65) | PKML3MBTL1NPC1RAB9ASNCA | |
| SCHEMBL5184275 | 0.77 | MAPT (0.57) | PKMNPC1RAB9AMAPTKDM4E | |
| SCHEMBL1535834 | 0.77 | MAPT (0.59) | PKML3MBTL1NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL9409572 | 0.74 | MAPT (0.53) | PKML3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799663-B1 | Modulators of HCV replication | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-08-01 | — | — | EP | claimed |