Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28485250 | 0.75 | ALDH1A1 (0.42) | ABCB1ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL23458987 | 0.75 | ALDH1A1 (0.42) | ABCB1ALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL23458984 | 0.75 | ALDH1A1 (0.42) | ABCB1ALDH1A1HSD17B10KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11731499 | 0.72 | KMT2A (0.39) | ALDH1A1KMT2AMEN1GAARECQL | |
| SCHEMBL17542008 | 0.70 | ABCB1 (0.43) | ABCB1KMT2AMEN1GAACYP2C9 | |
| SCHEMBL28879326 | 0.70 | ABCB1 (0.43) | ABCB1KMT2AMEN1GAACYP2C9 | |
| SCHEMBL17610289 | 0.69 | ABCB1 (0.43) | ABCB1ALDH1A1ELANETACR3PSEN1 | |
| SCHEMBL1189349 | 0.69 | ABCB1 (0.43) | ABCB1ALDH1A1ELANETACR3PSEN1 | |
| SCHEMBL27219845 | 0.69 | AGTR2 (0.41) | — | |
| SCHEMBL1226984 | 0.69 | ALDH1A1 (0.39) | ABCB1ALDH1A1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |