Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.64 |
| ▸ | AGXT | P21549 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724180 | 1.00 | LOXL2 (0.64) | LOXL2AGXTHDAC6HTR2BHTR1A | |
| SCHEMBL29405959 | 0.83 | LOXL2 (0.60) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL29405858 | 0.83 | LOXL2 (0.60) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL2249038 | 0.83 | LOXL2 (0.60) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL14075637 | 0.82 | LOXL2 (0.69) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL22971168 | 0.80 | LOXL2 (0.56) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL4432584 | 0.79 | LOXL2 (0.55) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL1680581 | 0.79 | LOXL2 (0.50) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL3026368 | 0.78 | LOXL2 (0.64) | LOXL2AGXTHTR2BHTR1AKDM4E | |
| SCHEMBL4149836 | 0.78 | LOXL2 (0.64) | LOXL2AGXTHTR2BHTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116637634-B | Preparation and application of furanmethanol compound hydrogenolysis catalyst | 南昌大学 | 2025-06-13 | — | — | CN | claimed |
| CN-117305863-A | Method for electrochemically synthesizing 3-benzofuranmethanol and analogues thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | claimed |
| CN-116637634-A | Preparation and application of furanmethanol compound hydrogenolysis catalyst | 南昌大学 | 2023-08-25 | — | — | CN | claimed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | claimed |
| EP-4691558-A2 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | University Court of The University of Dundee (GB) | 2026-02-11 | — | — | EP | disclosed |
| US-20250295789-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2025-09-25 | — | — | US | disclosed |
| EP-2857018-B1 | Treatment or prophylaxis of proliferative conditions | UNIV COURT OF THE UNIV OF DUNDEE (GB) | 2025-09-03 | — | — | EP | disclosed |
| CN-116637634-B | Preparation and application of furanmethanol compound hydrogenolysis catalyst | 南昌大学 | 2025-06-13 | — | — | CN | disclosed |
| US-12240812-B2 | Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof | Keythera (Suzhou) Pharmaceuticals Co. Ltd. (CN) | 2025-03-04 | — | — | US | disclosed |
| EP-3889134-B1 | COMPOUND FOR INHIBITING PGE2/EP4 SIGNALING TRANSDUCTION INHIBITING, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | KEYTHERA SUZHOU PHARMACEUTICALS CO LTD (CN) | 2024-09-25 | — | — | EP | disclosed |
| CN-118401503-A | Process for the preparation of benzofurans | 坎布雷普佛马可米兰有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-118359656-A | Copper-catalyzed stannization reaction method for carbon-oxygen bond cleavage of aryl methanol | 天津师范大学 | 2024-07-19 | — | — | CN | disclosed |
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0449523-A1 | Mercapto- or acylthio-trifluoromethyl amide derivatives and their use | E.R. SQUIBB & SONS, INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| WO-1991009023-A1 | N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |
| EP-0428437-A1 | 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-05-22 | — | — | EP | disclosed |
| EP-0304409-A1 | 5-Heterocyclic-substituted oxazolidine haloacetamides | MONSANTO COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0029311-B1 | AMINOALKYL BENZOFURAN DERIVATIVES, THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| EP-0029311-A1 | Aminoalkyl benzofuran derivatives, their production and compositions containing them | MERCK & CO. INC. (US) | 1981-05-27 | — | — | EP | disclosed |
| US-4238487-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250295789-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, BRCA1, UGT1A1 | LOXL2 1159/4885AGXT 2494/4885HDAC6 2292/4885 |
| US-12240812-B2 | Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof | PTGER4, PTGER1, PTGES | LOXL2 814/4885AGXT 3154/4885HDAC6 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.