Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | C1R | P00736 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536323 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1PTPN1MAOBS100A4 | |
| SCHEMBL28548550 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1PTPN1MAOBS100A4 | |
| SCHEMBL28277294 | 0.79 | — | — | |
| SCHEMBL28665179 | 0.78 | MAPK1 (0.37) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL6033614 | 0.78 | PTPN1 (0.43) | ALDH1A1TDP1PTPN1MAOBS100A4 | |
| SCHEMBL8689824 | 0.77 | NPC1 (0.31) | RAB9ASMN1; SMN2 | |
| SCHEMBL27122607 | 0.77 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL28898189 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1PTPN1MAOBS100A4 | |
| Hydrochloric Acid SCHEMBL28455293 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TDP1PTPN1MAOBS100A4 | |
| SCHEMBL28554886 | 0.74 | MAPK1 (0.34) | ALDH1A1GAAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431117-B2 | Sickled erythrocytes with anti-tumor agents induce tumor vaso-occlusion and tumoricidal effects | TERMAN DAVID S (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120195869-A1 | Sickled Erythrocytes with Anti-tumor Agents Induce Tumor Vaso-occlusion and Tumoricidal Effects | TERMAN DAVID S (US) | 2012-08-02 | — | — | US | disclosed |