Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261530 | 0.81 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8906766 | 0.75 | — | — | |
| SCHEMBL5011952 | 0.72 | — | — | |
| SCHEMBL3995632 | 0.71 | HSD17B10 (0.38) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7257246 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL20240638 | 0.71 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7257319 | 0.71 | — | — | |
| SCHEMBL4266709 | 0.70 | KIF11 (0.33) | — | |
| SCHEMBL8866729 | 0.70 | — | — | |
| SCHEMBL5134033 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831088-A | OSMYLATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1998-11-03 | — | — | US | disclosed |
| EP-0804439-A1 | BETA, BETA '-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM BETA ,BETA '-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-11-05 | — | — | EP | disclosed |
| US-5648485-A | PORPHYRIN COMPOUNDS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-07-15 | — | — | US | disclosed |
| WO-1996013504-A1 | β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1996-05-09 | — | — | WO | disclosed |