Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | HPGD | P15428 | 10/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 4/20 | 0.60 |
| ▸ | CASP7 | P55210 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650322 | 0.86 | KDM4E (0.70) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL3994327 | 0.85 | SRC (0.64) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL29752815 | 0.85 | SRC (0.64) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL72225 | 0.85 | SRC (0.64) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL13840542 | 0.85 | SRC (0.64) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL7110939 | 0.85 | SRC (0.60) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL10349724 | 0.84 | SRC (0.62) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2528490 | 0.83 | SRC (0.53) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL29577443 | 0.83 | SRC (0.53) | KDM4EMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL24807336 | 0.83 | SRC (0.64) | KDM4EMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709721-B2 | Fluorescent molecule and method for detecting target nucleic acid | RIKEN (JP) | 2014-04-29 | — | — | US | disclosed |
| EP-2484671-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | Riken (JP) | 2012-08-08 | — | — | EP | disclosed |
| EP-2484671-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | Riken (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | RIKEN (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | RIKEN (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | RIKEN (JP) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196377-A1 | FLUORESCENT MOLECULE AND METHOD FOR DETECTING TARGET NUCLEIC ACID | DNTT, POLL, POLRMT | KDM4E 3822/4885MAPT 4731/4885RAB9A 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.