SCHEMBL2528490

SCHEMBL2528490

Cc1c(CC(=O)ON2C(=O)CCC2=O)c(=O)oc2cc(N)ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.53
PSMB8 P28062 2/20 0.51
PSMB5 P28074 1/20 0.51
KDM4E B2RXH2 10/20 0.50
MAPT P10636 3/20 0.50
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 8/20 0.49
HSD17B10 Q99714 7/20 0.49
GLA P06280 4/20 0.49
CASP1 P29466 3/20 0.49
CASP7 P55210 3/20 0.49
ATM Q13315 2/20 0.49
LMNA P02545 1/20 0.49
THRB P10828 1/20 0.49
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 8/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577443 1.00 SRC (0.53) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL8054975 0.90 PSMB8 (0.62) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL29385493 0.88 KDM4E (0.57) PSMB8PSMB5KDM4EMAPTRAB9A
SCHEMBL593432 0.88 KDM4E (0.57) PSMB8PSMB5KDM4EMAPTRAB9A
SCHEMBL1264617 0.85 SRC (0.46) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL17941700 0.85 KDM4E (0.58) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL19465287 0.85 SRC (0.46) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL5273872 0.84 PSMB8 (0.51) PSMB8PSMB5KDM4EMAPTRAB9A
SCHEMBL1518388 0.84 SRC (0.44) SRCPSMB8PSMB5KDM4EMAPT
SCHEMBL22030047 0.84 PSMB8 (0.54) PSMB8PSMB5KDM4EMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173481-B1 INACTIVATED CYTOKINES FOR IMMUNISATION NEOVACS (FR) 2008-11-26 EP claimed
US-20050180950-A1 Chemically modified TNF-alpha NEOVACS (FR) 2005-08-18 US claimed
EP-1173481-A1 INACTIVATED CYTOKINES FOR IMMUNISATION NEOVACS (FR) 2002-01-23 EP claimed
WO-2000064937-A1 INACTIVATED CYTOKINES FOR IMMUNISATION NEOVACS (FR) 2000-11-02 WO claimed
US-5652093-A Analogues of reporter groups as background reducers in binding assays APROGENEX, INC. (US) 1997-07-29 US claimed
US-5501952-A Analogues of reporter groups as background reducers in hybridization assays APROGENEX, INC. (US) 1996-03-26 US claimed
WO-1995002699-A1 ANALOGUES OF REPORTER GROUPS AS BACKGROUNG REDUCERS IN HYBRIDIZATION ASSAYS APROGENEX, INC. (US) 1995-01-26 WO claimed
US-20260132459-A1 COMPOSITIONS AND METHODS FOR PREPARING NUCLEIC ACID NANOSTRUCTURES USING COMPACTION OLIGONUCLEOTIDES ELEMENT BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-20260132442-A1 SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS ELEMENT BIOSCIENCES INC (US) 2026-05-14 US disclosed
EP-4739794-A1 METHODS, COMPOSITONS, AND SYSTEMS FOR ANALYTE DETECTION Stellaromics, Inc. (US) 2026-05-13 EP disclosed
US-20260125743-A1 COMPOSITIONS AND METHODS FOR TARGET DETECTION STELLAROMICS INC (US) 2026-05-07 US disclosed
US-20260125751-A1 CYANINE DERIVATIVES AND RELATED USES ELEMENT BIOSCIENCES INC (US) 2026-05-07 US disclosed
US-20260125671-A1 METHODS FOR GENERATING CIRCULAR NUCLEIC ACID MOLECULES ELEMENT BIOSCIENCES INC (US) 2026-05-07 US disclosed
WO-2000064937-A1 INACTIVATED CYTOKINES FOR IMMUNISATION NEOVACS (FR) 2000-11-02 WO disclosed
WO-2000018962-A9 METHODS AND COMPOSITIONS FOR AMPLIFYING DETECTABLE SIGNALS IN SPECIFIC BINDING ASSAYS AFFYMETRIX INC (US) 2000-08-24 WO disclosed
EP-0999285-A1 Methods and compositions for amplifying detectable signals in specific binding assays Affymetrix, Inc. (a California Corporation) (US) 2000-05-10 EP disclosed
US-5652093-A Analogues of reporter groups as background reducers in binding assays APROGENEX, INC. (US) 1997-07-29 US disclosed
US-5501952-A Analogues of reporter groups as background reducers in hybridization assays APROGENEX, INC. (US) 1996-03-26 US disclosed
WO-1995002699-A1 ANALOGUES OF REPORTER GROUPS AS BACKGROUNG REDUCERS IN HYBRIDIZATION ASSAYS APROGENEX, INC. (US) 1995-01-26 WO disclosed
US-5376531-A Detecting gastrointestinal tumor by contacting the sampling with an octasaccharide, measuring by enzyme-linked immunosorbent assays NORTHWESTERN UNIVERSITY (US) 1994-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125743-A1 COMPOSITIONS AND METHODS FOR TARGET DETECTION SPPL2B, SPPL2A, SRMS SRC 287/4885PSMB8 4128/4885PSMB5 3645/4885
US-20260125671-A1 METHODS FOR GENERATING CIRCULAR NUCLEIC ACID MOLECULES POLM, DNMT3A, POLRMT SRC 1502/4885PSMB8 1596/4885PSMB5 3073/4885
US-20260125751-A1 CYANINE DERIVATIVES AND RELATED USES NSUN2, NSUN3, AS3MT SRC 997/4885PSMB8 4436/4885PSMB5 4408/4885
US-20260132442-A1 SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS POLM, RNGTT, CPSF6 SRC 2744/4885PSMB8 1848/4885PSMB5 3306/4885
US-20260132459-A1 COMPOSITIONS AND METHODS FOR PREPARING NUCLEIC ACID NANOSTRUCTURES USING COMPACTION OLIGONUCLEOTIDES PCNA, POLM, RNGTT SRC 343/4885PSMB8 3478/4885PSMB5 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.