Epiryanodine

Epiryanodine

SCHEMBL118946

CC(C)[C@@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@@]2(O)[C@@]3(C)C[C@]4(O)O[C@@]5([C@H](O)[C@@H](C)CC[C@]35O)[C@@]2(O)[C@@]14C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RYR1 P21817 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epiryanodine SCHEMBL159872 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL5933502 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL20100627 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL13912554 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL20104624 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL31236365 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL25722480 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL13479886 1.00 RYR1 (1.00) RYR1
Epiryanodine SCHEMBL5820916 0.99 RYR1 (0.98) RYR1
Epiryanodine SCHEMBL4318989 0.99 RYR1 (0.98) RYR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18783 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP claimed
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
EP-4687444-A1 IMPROVED WAXY DELIVERY FORMS FOR OILY AGRONOMIC ACTIVE INGREDIENTS AND METHOD OF PREPARATION CLEVER BIOSCIENCE S.R.L. (IT) 2026-02-11 EP claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP claimed
US-5413907-A Isolation of DNA codes for ryanodine receivers for diagnosis THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1995-05-09 US claimed
EP-0639986-A1 TOPICAL OPHTHALMIC COMPOSITIONS COMPRISING A COMBINATION OF CALCIUM ANTAGONISTS WITH KNOWN ANTIGLAUCOMA AGENTS ALCON LABORATORIES, INC. (US) 1995-03-01 EP claimed
EP-0494193-B1 DIAGNOSIS FOR MALIGNANT HYPERTHERMIA UNIV TORONTO (CA) 1994-12-21 EP claimed
WO-1993023082-A1 TOPICAL OPHTHALMIC COMPOSITIONS COMPRISING A COMBINATION OF CALCIUM ANTAGONISTS WITH KNOWN ANTIGLAUCOMA AGENTS ALCON LABORATORIES, INC. (US) 1993-11-25 WO claimed
US-5242801-A Diagnosing malignant hyperthermia susceptibility by detection of abnormal proteolytic enzyme digestion fragments of the ryanodine receptor UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1993-09-07 US claimed
US-5171217-A Injecting drug carried on microparticles of biocompatible biodegradable polymer into vessel wall under directed pressure INDIANA UNIVERSITY FOUNDATION (US) 1992-12-15 US claimed
WO-1992018499-A1 NOVEL ESTER DERIVATIVES OF RYANODINE AND DEHYDRORYANODINE INDIANA UNIVERSITY FOUNDATION (US) 1992-10-29 WO claimed
WO-1992015282-A2 COMPOSITION AND METHOD FOR DELIVERY OF DRUGS INDIANA UNIVERSITY FOUNDATION (US) 1992-09-17 WO claimed
EP-0494193-A1 DIAGNOSIS FOR MALIGNANT HYPERTHERMIA. UNIV TORONTO (CA) 1992-07-15 EP claimed
WO-1991004328-A1 DIAGNOSIS FOR MALIGNANT HYPERTHERMIA THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1991-04-04 WO claimed