Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR1 | P21817 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epiryanodine SCHEMBL159872 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL5933502 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL20100627 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL118946 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL13912554 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL31236365 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL25722480 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL13479886 | 1.00 | RYR1 (1.00) | RYR1 | |
| Epiryanodine SCHEMBL5820916 | 0.99 | RYR1 (0.98) | RYR1 | |
| Epiryanodine SCHEMBL4318989 | 0.99 | RYR1 (0.98) | RYR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392360-B2 | Synthetic route to anhydroryanodol, ryanodol and structural analogues | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180118706-A1 | Synthetic Route To Anhydroryanodol, Ryanodol And Structural Analogues | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118706-A1 | Synthetic Route To Anhydroryanodol, Ryanodol And Structural Analogues | ADCY4, TRHDE, ADCY8 | RYR1 105/4885 |
| US-10392360-B2 | Synthetic route to anhydroryanodol, ryanodol and structural analogues | ADCY4, ADCY8, TALDO1 | RYR1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.