Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894873 | 0.92 | P4HTM (0.40) | MCL1BCL2L1PTGS2PTGS1EGFR | |
| SCHEMBL11895142 | 0.91 | MCL1 (0.42) | MCL1BCL2L1KAT6APTGS2PTGS1 | |
| SCHEMBL11894666 | 0.90 | MYC (0.43) | PARP1CYP19A1 | |
| SCHEMBL11894516 | 0.88 | MAPT (0.44) | KAT6APARP1CYP19A1 | |
| SCHEMBL11895177 | 0.85 | CYP19A1 (0.40) | PARP1CYP19A1 | |
| SCHEMBL11894532 | 0.83 | PLA2G2A (0.41) | MCL1BCL2L1PTGS2PTGS1EGFR | |
| SCHEMBL11894570 | 0.83 | CASP1 (0.46) | — | |
| SCHEMBL11895117 | 0.82 | PLA2G2A (0.41) | PARP1 | |
| SCHEMBL11895186 | 0.82 | PHGDH (0.41) | EGFRCYP19A1 | |
| SCHEMBL11894883 | 0.80 | MAPT (0.45) | EGFRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487175-A1 | PHARMACEUTICAL PRODUCT CONTAINING AROMATIC HETEROCYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND | CYP2C18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2B6 | MCL1 3520/4885BCL2L1 3300/4885KAT6A 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.