SCHEMBL11897019

SCHEMBL11897019

CCN(CC)C(=O)C(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
DPP4 P27487 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HTT P42858 4/20 0.33
KMT2A Q03164 3/20 0.33
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
HTR1A P08908 2/20 0.32
EHMT2 Q96KQ7 3/20 0.32
EHMT1 Q9H9B1 3/20 0.32
ABCB11 O95342 2/20 0.32
GSDMD P57764 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28200519 0.91 LMNA (0.34) LMNAMMP1MMP2MMP3MMP8
Diethylamine SCHEMBL28200518 0.89 TP53 (0.35) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11740017 0.82 DPP4 (0.37) LMNAMMP1MMP2MMP3MMP8
SCHEMBL2921860 0.81 LMNA (0.39) LMNAMMP1MMP2MMP3MMP8
SCHEMBL10671732 0.81 LMNA (0.39) LMNAMMP1MMP2MMP3MMP8
SCHEMBL10673924 0.81 LMNA (0.39) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11748479 0.80 ALDH1A1 (0.41) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11748525 0.80 ALDH1A1 (0.36) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11746872 0.80 LMNA (0.31) LMNAMMP1MMP2MMP3MMP8
SCHEMBL11231800 0.80 LMNA (0.31) LMNAMMP1MMP2MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603143-A Synthesis method of oxazine 294 impurity 杭州小蓓医药科技有限公司 2024-02-27 CN claimed
CN-107573242-A A kind of preparation method of ethyl bromide difluoride 盐城顺恒化工有限公司 2018-01-12 CN claimed
CN-102875379-A Industrialized synthetic method of ethyl difuoroacetate SHANGHAI PINWO CHEMICAL CO LTD 2013-01-16 CN claimed
CN-102311343-A Processing technique of ethyl difluoroacetate RUGAO JINLING CHEMICAL CO LTD 2012-01-11 CN claimed
CN-117986113-A Preparation method of ethyl difluoroacetate 安顺学院 2024-05-07 CN disclosed
CN-117603143-A Synthesis method of oxazine 294 impurity 杭州小蓓医药科技有限公司 2024-02-27 CN disclosed
CN-117603143-A Synthesis method of oxazine 294 impurity 杭州小蓓医药科技有限公司 2024-02-27 CN disclosed
CN-115894191-B Method for coproducing trifluoroacetone and difluoroacetate 山东华安新材料有限公司 2024-01-30 CN disclosed
CN-117447348-A Synthesis method of difluoroacetamide compound 辽宁优创植物保护有限公司 2024-01-26 CN disclosed
CN-115894191-A Method for co-producing trifluoroacetone and difluoroacetic acid ester 山东华安新材料有限公司 2023-04-04 CN disclosed
CN-218248556-U Difluoro acetoacetic ester apparatus for producing 福建久策气体股份有限公司 2023-01-10 CN disclosed
CN-115368236-A Preparation method of ethyl difluoroacetate 江苏蓝色星球环保科技股份有限公司 2022-11-22 CN disclosed
CN-103113220-A Synthesis method of difluoroacetate ester JUHUA GROUP TECHNOLOGY CT 2013-05-22 CN disclosed
US-8431513-B2 Phenolic compound and recording material NIPPON SODA CO., LTD. (JP) 2013-04-30 US disclosed
CN-102875379-A Industrialized synthetic method of ethyl difuoroacetate SHANGHAI PINWO CHEMICAL CO LTD 2013-01-16 CN disclosed
US-20120204763-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL NIPPON SODA CO., LTD. 2012-08-16 US disclosed
EP-2484663-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL Nippon Soda Co., Ltd. (JP) 2012-08-08 EP disclosed
CN-102574784-A Phenolic compound and recording material NIPPON SODA CO 2012-07-11 CN disclosed
CN-102311343-A Processing technique of ethyl difluoroacetate RUGAO JINLING CHEMICAL CO LTD 2012-01-11 CN disclosed
CN-102311343-A Processing technique of ethyl difluoroacetate RUGAO JINLING CHEMICAL CO LTD 2012-01-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120204763-A1 PHENOLIC COMPOUND AND RECORDING MATERIAL OR10J3, OR51E2, H1-4 LMNA 999/4885MMP1 1043/4885MMP2 2692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.