Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.36 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11897718 | 0.87 | PTPN1 (0.40) | KMT2AMEN1MGLLCA12CA1 | |
| SCHEMBL11897734 | 0.84 | FOLH1 (0.53) | KMT2AMEN1MEP1BMEP1AFOLH1 | |
| SCHEMBL1479630 | 0.82 | F10 (0.38) | KMT2AMEN1GAAMEP1B | |
| SCHEMBL11897625 | 0.80 | ALDH1A1 (0.37) | KMT2AMEN1MGLLCA12CA1 | |
| SCHEMBL1478744 | 0.76 | SMN1; SMN2 (0.49) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11897877 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1GAAMGLLCA12 | |
| SCHEMBL348507 | 0.74 | ALDH1A1 (0.58) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL7443680 | 0.73 | BCL2 (0.47) | GAAPRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL38652489 | 0.73 | BCL2 (0.47) | GAAPRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL38652541 | 0.70 | KAT6A (0.48) | KMT2AMEN1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699606-B1 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORP (JP) | 2016-09-28 | — | — | EP | disclosed |
| EP-2699606-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | Bridgestone Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012135451-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-10-04 | — | — | WO | disclosed |
| EP-2483317-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |