Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MEP1B | Q16820 | 11/20 | 0.52 |
| ▸ | MEP1A | Q16819 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11897715 | 0.87 | FOLH1 (0.56) | FOLH1MEP1BMEP1ASMN1; SMN2HTT | |
| SCHEMBL11897692 | 0.84 | KMT2A (0.41) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| SCHEMBL168738 | 0.83 | FOLH1 (0.59) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| SCHEMBL29630981 | 0.83 | FOLH1 (0.59) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| SCHEMBL1478744 | 0.82 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL15067497 | 0.81 | FOLH1 (0.58) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29690742 | 0.81 | FOLH1 (0.58) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| SCHEMBL4836068 | 0.80 | MEN1 (0.63) | FOLH1MEP1BMEP1AMEN1KMT2A | |
| SCHEMBL11897476 | 0.80 | ALDH1A1 (0.52) | MEP1BMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL15142867 | 0.79 | FOLH1 (0.54) | FOLH1MEP1BMEP1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699606-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | Bridgestone Corporation (JP) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012135451-A2 | POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2012-10-04 | — | — | WO | disclosed |
| EP-2483317-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |