Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.62 |
| ▸ | TUBB | P07437 | 1/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.62 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.62 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.62 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.62 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.62 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chalcone SCHEMBL11898044 | 1.00 | ALDH1A1 (0.62) | ALDH1A1AOX1TNFRSF1ACYP1B1CYP1A1 | |
| SCHEMBL31233430 | 0.91 | TUBB1 (0.73) | ALDH1A1CYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL31233067 | 0.91 | TUBB1 (0.73) | ALDH1A1CYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL25279622 | 0.91 | TUBB1 (0.73) | ALDH1A1CYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL28739804 | 0.91 | TUBB1 (0.73) | ALDH1A1CYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL25211728 | 0.91 | TUBB1 (0.73) | ALDH1A1CYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL30384079 | 0.84 | TUBB1 (0.79) | TNFRSF1ACYP1B1CYP1A1CYP1A2TUBB1 | |
| SCHEMBL25196076 | 0.84 | TUBB1 (0.79) | TNFRSF1ACYP1B1CYP1A1CYP1A2TUBB1 | |
| Isovanillin SCHEMBL28288925 | 0.84 | ALDH1A1 (0.83) | ALDH1A1AOX1CYP1A2TUBB1TUBB4A | |
| SCHEMBL25285354 | 0.84 | TUBB4A (0.67) | ALDH1A1TNFRSF1ACYP1B1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-2029527-B1 | MODIFIED CHALCONE COMPOUNDS AS ANTIMITOTIC AGENTS | ARIZONA BIOMEDICAL RES COMMISSION (US) | 2012-08-08 | — | — | EP | disclosed |