Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11898299 | 1.00 | KMT2A (0.39) | KMT2AMAPTKCNN4KIF11ALDH1A1 | |
| SCHEMBL11898338 | 1.00 | KMT2A (0.39) | KMT2AMAPTKCNN4KIF11ALDH1A1 | |
| SCHEMBL1822224 | 0.79 | MAPT (0.63) | KMT2AMAPTKCNN4ALDH1A1 | |
| SCHEMBL11898285 | 0.77 | HDAC1 (0.43) | — | |
| SCHEMBL11898353 | 0.77 | CFTR (0.33) | KCNN4 | |
| SCHEMBL11898435 | 0.76 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL28014057 | 0.73 | CA1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL11898380 | 0.73 | MLYCD (0.39) | KMT2AALDH1A1 | |
| SCHEMBL11898336 | 0.72 | PPARA (0.40) | KIF11 | |
| SCHEMBL29083516 | 0.71 | CES2 (0.35) | KMT2AALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094638-B1 | 2-ARYL-2-FLUOROPROPANOIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-08-08 | — | — | EP | claimed |