⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57383 | 0.97 | — | — | |
| SCHEMBL1602869 | 0.97 | — | — | |
| SCHEMBL2983504 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6283604 | 0.94 | — | — | |
| Methane SCHEMBL705841 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL1047427 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL1047426 | 0.94 | — | — | |
| SCHEMBL69143 | 0.90 | — | — | |
| SCHEMBL3504272 | 0.88 | NOS2 (0.36) | — | |
| SCHEMBL18534321 | 0.88 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101671357-B | (S)-Alpha, Alpha-fluorine-containing diaryl-2-pyrrolidine methanol derivative as well as preparation and applications thereof | UNIV ZHEJIANG TECHNOLOGY | 2012-11-14 | — | — | CN | claimed |
| CN-101671357-A | (S)-Alpha, Alpha-fluorine-containing diaryl-2-pyrrolidine methanol derivative as well as preparation and applications thereof | UNIV ZHEJIANG TECHNOLOGY | 2010-03-17 | — | — | CN | claimed |
| EP-0188235-B1 | PRODUCTION OF OPTICALLY PURE ORGANOBORANES | Aldrich Chemical Company, Inc. (US) | 1991-12-11 | — | — | EP | claimed |
| EP-0188235-A2 | Production of optically pure organoboranes | Aldrich Chemical Company, Inc. (US) | 1986-07-23 | — | — | EP | claimed |
| JP-5097735-A | — | — | None | — | — | JP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| CN-115805003-A | Novel amine compound, acid gas absorbent, method for removing acid gas, and acid gas removal device | 株式会社东芝 | 2023-03-17 | — | — | CN | disclosed |
| EP-4011396-A1 | RELEASABLE CONJUGATES | QuiaPEG Pharmaceuticals AB (SE) | 2022-06-15 | — | — | EP | disclosed |
| US-20220135544-A1 | PYRAZOLYL QUINOXALINE KINASE INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2022-05-05 | — | — | US | disclosed |
| EP-3592393-B1 | RELEASABLE CONJUGATES | QUIAPEG PHARMACEUTICALS AB (SE) | 2021-12-01 | — | — | EP | disclosed |
| CN-109342510-B | Chiral recognition method based on monomolecular electrical detection | 厦门大学 | 2020-09-25 | — | — | CN | disclosed |
| JP-H0597735-A | PRODUCTION OF OPTICALLY ACTIVE SECONDARY ALCOHOL | AJINOMOTO CO INC | 1993-04-20 | — | — | JP | disclosed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | disclosed |
| US-5166371-A | Catalytic epoxidation of allyl alcohol using a hydroperoxide | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0494816-A1 | 1,4-Dihydropyridine derivatives, process for their preparation and therapeutical composition containing them | LABORATOIRE L. LAFON (FR) | 1992-07-15 | — | — | EP | disclosed |
| EP-0472790-A1 | Asymmetric epoxidation using a chiral hydroperoxide | ARCO Chemical Technology, L.P. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-4248884-A | HYPOLIPEMIC AGENTS, PSYCHOSTIMULANTS | PHARMINDUSTRIE (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4248884-A | HYPOLIPEMIC AGENTS, PSYCHOSTIMULANTS | PHARMINDUSTRIE (FR) | 1981-02-03 | — | — | US | disclosed |
| EP-0022408-A1 | Derivatives of alpha-phenyl-2-pyrrolidine methanol and their salts, process for their preparation, use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1981-01-14 | — | — | EP | disclosed |