⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57383 | 1.00 | — | — | |
| SCHEMBL1602869 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6283604 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1047426 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1047427 | 0.97 | — | — | |
| Methane SCHEMBL1189865 | 0.97 | — | — | |
| SCHEMBL69143 | 0.93 | — | — | |
| SCHEMBL3504272 | 0.91 | NOS2 (0.36) | — | |
| Methane SCHEMBL705841 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL16777052 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800972-A | Chemical synthesis method of klebsiella toxin Tilimycin | 南京大学 | 2024-04-02 | — | — | CN | claimed |
| CN-102911106-A | Preparation method of L-N-Boc-high tryptophan methyl ester | SHANGHAI HEQUAN PHARMACEUTICAL RES DEV CO LTD | 2013-02-06 | — | — | CN | claimed |
| JP-9316077-A | — | — | None | — | — | JP | disclosed |
| CN-117800972-B | Chemical synthesis method of klebsiella toxin TILIMYCIN | 南京大学 | 2026-04-21 | — | — | CN | disclosed |
| CN-117800972-A | Chemical synthesis method of klebsiella toxin Tilimycin | 南京大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-117800972-A | Chemical synthesis method of klebsiella toxin Tilimycin | 南京大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-114409585-A | 2-oxopyrrolidine derivatives, process for preparing the same and process for preparing intermediates | 凯莱英医药集团（天津）股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-10336727-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180305336-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-10-25 | — | — | US | disclosed |
| US-10040779-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-2934145-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2017-11-15 | — | — | EP | disclosed |
| WO-2004081005-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2004-09-23 | — | — | WO | disclosed |
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1131288-A1 | PYRROLIDINE DERIVATIVES-CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| US-6166015-A | Pyrrolidine derivatives-CCR-3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000031032-A1 | PYRROLIDINE DERIVATIVES-CCR-3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-02 | — | — | WO | disclosed |
| JP-H09316077-A | NEW PURINE NUCLEOSIDE DERIVATIVE AND ITS PRODUCTION | NIPPON PAPER IND CO LTD | 1997-12-09 | — | — | JP | disclosed |
| US-5116842-A | Analgesics | GLAXO GROUP LIMITED (GB) | 1992-05-26 | — | — | US | disclosed |
| EP-0398720-A2 | Piperazine derivatives | GLAXO GROUP LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |
| CN-1037149-A | The preparation method of 3-alkenyl-1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid cpd | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-11-15 | — | — | CN | disclosed |